Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190344 | 1.00 | LSS (0.41) | LSSHPGDL3MBTL1KIF11ALDH1A1 | |
| SCHEMBL9190337 | 1.00 | LSS (0.41) | LSSHPGDL3MBTL1KIF11ALDH1A1 | |
| SCHEMBL9186042 | 0.96 | LSS (0.43) | LSSHPGDL3MBTL1KIF11ALDH1A1 | |
| SCHEMBL9186038 | 0.96 | LSS (0.43) | LSSHPGDL3MBTL1KIF11ALDH1A1 | |
| SCHEMBL9189170 | 0.93 | LSS (0.41) | LSSHPGDL3MBTL1KIF11ALDH1A1 | |
| SCHEMBL9189147 | 0.93 | LSS (0.41) | LSSHPGDL3MBTL1KIF11ALDH1A1 | |
| SCHEMBL9189161 | 0.93 | LSS (0.41) | LSSHPGDL3MBTL1KIF11ALDH1A1 | |
| SCHEMBL9187609 | 0.90 | LSS (0.45) | LSSHPGDL3MBTL1KIF11ALDH1A1 | |
| SCHEMBL9187604 | 0.90 | LSS (0.45) | LSSHPGDL3MBTL1KIF11ALDH1A1 | |
| SCHEMBL9187613 | 0.90 | LSS (0.45) | LSSHPGDL3MBTL1KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423520-B1 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GMBH (DE) | 1995-08-02 | — | — | EP | disclosed |
| EP-0423520-A2 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GmbH (DE) | 1991-04-24 | — | — | EP | disclosed |