Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91407 | 0.99 | TSHR (0.68) | TSHRMAPK1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL91587 | 0.90 | MAPK1 (0.63) | TSHRMAPK1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL4680215 | 0.90 | TSHR (0.67) | TSHRMAPK1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL10081941 | 0.85 | MAPK1 (0.57) | TSHRMAPK1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL77077 | 0.82 | MAPK1 (0.57) | TSHRMAPK1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL77674 | 0.81 | MAPK1 (0.56) | TSHRMAPK1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL10084297 | 0.80 | TSHR (0.52) | TSHRMAPK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL91408 | 0.79 | PDE5A (0.74) | TSHRMAPK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10085276 | 0.78 | MAPK1 (0.50) | TSHRMAPK1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL93110 | 0.78 | PDE5A (0.76) | TSHRMAPK1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8119645-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | TSHR 1440/4885MAPK1 2712/4885L3MBTL1 428/4885 |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | TSHR 1467/4885MAPK1 2690/4885L3MBTL1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.