Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609546 | 0.86 | MAPK1 (0.69) | MAPK1TSHRSMN1; SMN2GAAKMT2A | |
| SCHEMBL4255395 | 0.85 | MAPK1 (0.49) | MAPK1TSHRCSNK2A2CSNK2A1SMN1; SMN2 | |
| SCHEMBL91587 | 0.82 | MAPK1 (0.63) | MAPK1TSHRCSNK2A2CSNK2A1SMN1; SMN2 | |
| SCHEMBL13609557 | 0.81 | CYP1A2 (0.64) | MAPK1TSHRSMN1; SMN2GAAMAPT | |
| SCHEMBL10078987 | 0.80 | ATAD2 (0.50) | MAPK1TSHRSMN1; SMN2GAAKMT2A | |
| SCHEMBL27871368 | 0.80 | MAPK1 (0.40) | MAPK1TSHRCSNK2A2CSNK2A1SMN1; SMN2 | |
| SCHEMBL6922805 | 0.80 | CSNK2A2 (0.45) | MAPK1TSHRCSNK2A2CSNK2A1SMN1; SMN2 | |
| SCHEMBL10081941 | 0.80 | MAPK1 (0.57) | MAPK1TSHRCSNK2A2CSNK2A1SMN1; SMN2 | |
| SCHEMBL4255385 | 0.80 | L3MBTL1 (0.54) | MAPK1TSHRCSNK2A2CSNK2A1SMN1; SMN2 | |
| SCHEMBL10084294 | 0.79 | KMT2A (0.47) | MAPK1SMN1; SMN2GAAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119645-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | MAPK1 2690/4885TSHR 1467/4885CSNK2A2 2736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.