Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186234 | 1.00 | NFE2L2 (0.41) | NFE2L2HTR2AHTR2CKCNH2GLA | |
| SCHEMBL9184382 | 0.85 | MAPT (0.44) | NFE2L2ALDH1A1NPC1MAPTPTGS2 | |
| SCHEMBL9184392 | 0.85 | MAPT (0.44) | NFE2L2ALDH1A1NPC1MAPTPTGS2 | |
| SCHEMBL9187818 | 0.84 | NFE2L2 (0.46) | NFE2L2ALDH1A1L3MBTL1MEN1NPC1 | |
| SCHEMBL9188016 | 0.84 | NFE2L2 (0.46) | NFE2L2ALDH1A1L3MBTL1MEN1NPC1 | |
| SCHEMBL9182812 | 0.84 | NFE2L2 (0.47) | NFE2L2ADORA2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9182821 | 0.84 | NFE2L2 (0.47) | NFE2L2ADORA2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9435124 | 0.80 | CYP1A2 (0.44) | ADORA2AALDH1A1L3MBTL1KDM4ENPC1 | |
| SCHEMBL9435134 | 0.80 | CYP1A2 (0.44) | ADORA2AALDH1A1L3MBTL1KDM4ENPC1 | |
| SCHEMBL9261050 | 0.76 | SIRT2 (0.42) | BRD4MEN1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672036-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1995-09-20 | — | — | EP | claimed |
| WO-1994004513-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1994-03-03 | — | — | WO | claimed |
| EP-0672036-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994004513-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1994-03-03 | — | — | WO | disclosed |