Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528113 | 0.83 | PDE2A (0.47) | PDE2ACES2CES1MC4RCA1 | |
| SCHEMBL16976289 | 0.82 | PDE2A (0.46) | PDE2ASLC6A4CES2CES1MC4R | |
| SCHEMBL2090318 | 0.80 | PDE2A (0.49) | PDE2ASLC6A4CES2CES1MC4R | |
| SCHEMBL2763340 | 0.78 | HSD11B1 (0.47) | PDE2ASLC6A4CES2CES1CYP3A4 | |
| SCHEMBL906186 | 0.78 | HSD11B1 (0.47) | PDE2ASLC6A4CES2CES1CYP3A4 | |
| SCHEMBL3612320 | 0.78 | PDE2A (0.43) | PDE2ASLC6A4CES2CES1MC4R | |
| SCHEMBL3602797 | 0.78 | PDE2A (0.43) | PDE2ASLC6A4MC4R | |
| SCHEMBL2764096 | 0.78 | PDE2A (0.43) | PDE2ASLC6A4CES2CES1MC4R | |
| SCHEMBL16230332 | 0.78 | PDE2A (0.43) | PDE2ASLC6A4CES2CES1MC4R | |
| SCHEMBL3595268 | 0.78 | PDE2A (0.43) | PDE2ASLC6A4MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674651-A1 | SUBSTITUTED 6-AZAANDROSTENONES | GLAXO WELLCOME INC. (US) | 1995-10-04 | — | — | EP | disclosed |