SCHEMBL9188447

SCHEMBL9188447

COC(=O)N1c2ccccc2C=CC1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
P2RX4 Q99571 7/20 0.55
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 4/20 0.44
TSHR P16473 3/20 0.41
MAPK1 P28482 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
P2RX1 P51575 1/20 0.40
P2RX3 P56373 1/20 0.40
P2RX7 Q99572 1/20 0.40
BCHE P06276 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
GAA P10253 1/20 0.37
SCN4A P35499 1/20 0.37
SCN5A Q14524 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9187854 0.87 SMN1; SMN2 (0.80) LMNASMN1; SMN2P2RX4MEN1KMT2A
SCHEMBL9188247 0.86 SMN1; SMN2 (0.82) LMNASMN1; SMN2P2RX4MEN1KMT2A
SCHEMBL22262397 0.83 MEN1 (0.64) LMNASMN1; SMN2P2RX4MEN1KMT2A
SCHEMBL29659899 0.83 MEN1 (0.64) LMNASMN1; SMN2P2RX4MEN1KMT2A
SCHEMBL5862606 0.83 SMN1; SMN2 (0.62) LMNASMN1; SMN2P2RX4MEN1KMT2A
SCHEMBL29300312 0.82 SMN1; SMN2 (0.51) LMNASMN1; SMN2P2RX4MEN1KMT2A
SCHEMBL11728362 0.77 SMN1; SMN2 (0.82) LMNASMN1; SMN2P2RX4MEN1KMT2A
SCHEMBL23705539 0.75 SMN1; SMN2 (1.00) LMNASMN1; SMN2P2RX4MEN1KMT2A
SCHEMBL367474 0.75 SMN1; SMN2 (1.00) LMNASMN1; SMN2P2RX4MEN1KMT2A
SCHEMBL563346 0.75 SMN1; SMN2 (0.56) LMNASMN1; SMN2P2RX4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4224823-A None JP disclosed
JP-4311723-A None JP disclosed
EP-0490364-B1 Process for producing polyisoimide CHISSO CORP (JP) 1995-09-06 EP disclosed
US-5294696-A Process for producing polyisoimide CHISSO CORPORATION (JP) 1994-03-15 US disclosed
JP-H04311723-A PRODUCTION OF POLYAMIDE CHISSO CORP 1992-11-04 JP disclosed
JP-H04224823-A PRODUCTION OF PHOTOSENSITIVE RESIN COMPOSITION CHISSO CORP 1992-08-14 JP disclosed
EP-0490364-A2 Process for producing polyisoimide CHISSO CORPORATION (JP) 1992-06-17 EP disclosed