Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.65 |
| ▸ | GMNN | O75496 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | THPO | P40225 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CETP | P11597 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | UBE2N | P61088 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796385 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL1964586 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL4287325 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL313894 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL2312898 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL10571108 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL25243382 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL2233834 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL1964037 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL918041 | 1.00 | LMNA (0.65) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889890-B2 | Ketal esters of oxocarboxylic acids and process of making | SEGETIS, INC. (US) | 2014-11-18 | — | — | US | claimed |
| US-20120323024-A1 | KETAL ESTERS OF OXOCARBOXYLIC ACIDS AND PROCESS OF MAKING | SEGETIS, INC. (US) | 2012-12-20 | — | — | US | claimed |
| WO-2011032095-A1 | KETAL ESTERS OF OXOCARBOXYLIC ACIDS AND PROCESS OF MAKING | SEGETIS, INC. (US) | 2011-03-17 | — | — | WO | claimed |
| US-5446033-A | Antitumor agent; storage stability, antiseptic, chemical resistance, by-product inhibition | ASTA MEDICA AG (DE) | 1995-08-29 | — | — | US | claimed |
| EP-0248858-B1 | NOVEL PHOSPHO-COMPOUNDS AND MEDICAMENTS CONTAINING THESE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1990-02-28 | — | — | EP | claimed |
| EP-0248858-A1 | NOVEL PHOSPHO-COMPOUNDS AND MEDICAMENTS CONTAINING THESE. | MAX PLANCK GESELLSCHAFT (DE) | 1987-12-16 | — | — | EP | claimed |
| WO-1987003596-A2 | NOVEL PHOSPHO-COMPOUNDS AND MEDICAMENTS CONTAINING THESE | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSC (DE) | 1987-06-18 | — | — | WO | claimed |
| EP-0224925-A2 | Phosphorous compounds and medicines containing them | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1987-06-10 | — | — | EP | claimed |
| US-20250368983-A1 | CONTROLLING FOR TAGMENTATION SEQUENCING LIBRARY INSERT SIZE USING ARCHAEAL HISTONE-LIKE PROTEINS | KAPA BIOSYSTEMS INC (US) | 2025-12-04 | — | — | US | disclosed |
| EP-4581153-A1 | IMPROVEMENTS TO NEXT-GENERATION TARGET ENRICHMENT PERFORMANCE | F. Hoffmann-La Roche AG (CH) | 2025-07-09 | — | — | EP | disclosed |
| EP-4547839-A1 | CONTROLLING FOR TAGMENTATION SEQUENCING LIBRARY INSERT SIZE USING ARCHAEAL HISTONE-LIKE PROTEINS | Kapa Biosystems, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119895049-A | Improvements to next generation target enrichment performance | 豪夫迈·罗氏有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119497755-A | Control of library insert size for fragmentation and tag sequencing using archaebacteria histone-like proteins | 卡帕生物系统公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2024046992-A1 | IMPROVEMENTS TO NEXT-GENERATION TARGET ENRICHMENT PERFORMANCE | F. HOFFMANN-LA ROCHE AG (CH) | 2024-03-07 | — | — | WO | disclosed |
| EP-0230575-A2 | Medicament active against tumours, containing hexadecylphosphocholine | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1987-08-05 | — | — | EP | disclosed |
| WO-1987003480-A2 | MEDICAMENT WITH ANTI-TUMORAL ACTION CONTAINING HEXADECYLPHOSPHOCHOLINE | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSC (DE) | 1987-06-18 | — | — | WO | disclosed |
| WO-1987003596-A2 | NOVEL PHOSPHO-COMPOUNDS AND MEDICAMENTS CONTAINING THESE | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSC (DE) | 1987-06-18 | — | — | WO | disclosed |
| EP-0225608-A2 | Medicine | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1987-06-16 | — | — | EP | disclosed |
| EP-0224925-A2 | Phosphorous compounds and medicines containing them | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1987-06-10 | — | — | EP | disclosed |
| US-4101589-A | SURFACTANTS, LUBRICANTS, URETHANES, ALKYD RESINS | PILOT CHEMICAL COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120323024-A1 | KETAL ESTERS OF OXOCARBOXYLIC ACIDS AND PROCESS OF MAKING | AKR1C3, OXER1, ACSL6 | LMNA 2114/4885CYP2D6 99/4885SPHK1 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.