Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785534 | 0.81 | CYP3A4 (0.59) | CYP3A4GABRA1GABRB2TRPA1 | |
| SCHEMBL9051530 | 0.80 | CYP3A4 (0.48) | CYP3A4GABRA1GABRB2TRPA1 | |
| SCHEMBL9585916 | 0.79 | CYP3A4 (0.48) | CYP3A4GABRA1GABRB2TRPA1 | |
| SCHEMBL4935799 | 0.78 | CYP3A4 (0.47) | CYP3A4GABRA1GABRB2TRPA1 | |
| SCHEMBL28151572 | 0.75 | CYP3A4 (0.57) | CYP3A4GABRA1GABRB2TRPA1 | |
| SCHEMBL471856 | 0.75 | CYP3A4 (0.52) | CYP3A4GABRA1GABRB2TRPA1 | |
| SCHEMBL28588773 | 0.74 | CYP3A4 (0.55) | CYP3A4GABRA1GABRB2TRPA1 | |
| SCHEMBL112207 | 0.73 | CYP3A4 (0.46) | CYP3A4GABRA1GABRB2TRPA1 | |
| SCHEMBL5574050 | 0.71 | GABRA1 (0.45) | CYP3A4GABRA1GABRB2 | |
| SCHEMBL11443931 | 0.71 | GABRA1 (0.39) | CYP3A4GABRA1GABRB2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472081-B1 | Carbonic acid groups containing copolymers, their preparation and their use as a thickener | HOECHST AG (DE) | 1995-11-08 | — | — | EP | claimed |
| US-5109091-A | COPOLYMERS CONTAINING CARBOXYL GROUPS, THEIR PREPARATION, AND THEIR USE AS THICKENERS | HOECHST AG (DE) | 1992-04-28 | — | — | US | claimed |
| US-5109091-A | COPOLYMERS CONTAINING CARBOXYL GROUPS, THEIR PREPARATION, AND THEIR USE AS THICKENERS | HOECHST AG (DE) | 1992-04-28 | — | — | US | disclosed |