Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188709 | 1.00 | KMT2A (0.56) | KMT2AMEN1XDHTDP2CASP7 | |
| SCHEMBL8491228 | 0.83 | MEN1 (0.64) | KMT2AMEN1MAPTHRH3ALDH1A1 | |
| SCHEMBL7362683 | 0.80 | MEN1 (0.66) | KMT2AMEN1MAPTHRH3ALDH1A1 | |
| SCHEMBL79547 | 0.80 | MEN1 (0.66) | KMT2AMEN1MAPTHRH3ALDH1A1 | |
| SCHEMBL1598877 | 0.80 | MEN1 (0.66) | KMT2AMEN1MAPTHRH3ALDH1A1 | |
| SCHEMBL6132768 | 0.80 | MEN1 (0.54) | KMT2AMEN1MAPTHRH3ALDH1A1 | |
| SCHEMBL6132766 | 0.80 | MEN1 (0.54) | KMT2AMEN1MAPTHRH3ALDH1A1 | |
| SCHEMBL8596084 | 0.80 | MEN1 (0.54) | KMT2AMEN1MAPTHRH3ALDH1A1 | |
| SCHEMBL9186135 | 0.79 | KMT2A (0.55) | KMT2AMEN1MAPTTDP1HRH3 | |
| SCHEMBL9186136 | 0.79 | KMT2A (0.55) | KMT2AMEN1MAPTTDP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672036-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994004513-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1994-03-03 | — | — | WO | disclosed |