Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13454071 | 0.88 | GAA (0.62) | GAAMAPTHTTTDP1ALOX5 | |
| SCHEMBL12676484 | 0.86 | MAPT (0.47) | GAAMAPTADAMTS5DRD2ALOX5 | |
| SCHEMBL12676478 | 0.86 | ALOX5 (0.54) | GAAMAPTHTTALOX5MAOB | |
| SCHEMBL9162305 | 0.82 | GAA (0.52) | GAAMAPTHTTTDP1ALOX5 | |
| SCHEMBL12676472 | 0.81 | GAA (0.49) | GAAMAPTHTTADAMTS5ALDH1A1 | |
| SCHEMBL14941711 | 0.80 | HTR2C (0.55) | GAAMAPTDRD2NPC1POLB | |
| SCHEMBL12676485 | 0.80 | GAA (0.47) | GAAMAPTHTTADAMTS5ALOX5 | |
| SCHEMBL13454072 | 0.80 | GAA (0.51) | GAAMAPTHTTALDH1A1FFAR4 | |
| SCHEMBL9163336 | 0.79 | ALOX5 (0.56) | GAAMAPTHTTALOX5MAOB | |
| SCHEMBL12676477 | 0.78 | MAPT (0.60) | GAAMAPTTDP1L3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381291-B1 | Oximino ether compounds | SHELL INT RESEARCH (NL) | 1995-08-23 | — | — | EP | disclosed |
| EP-0381291-A1 | Oximino ether compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-08-08 | — | — | EP | disclosed |