SCHEMBL9189869

SCHEMBL9189869

Clc1nc(OC(Cl)(Cl)Cl)nc(OC(Cl)(Cl)Cl)n1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7804064 0.94 ALDH1A1 (0.44) ALDH1A1ALOX15TSHRCYP1A2
SCHEMBL9188446 0.84
SCHEMBL9184504 0.80
SCHEMBL9185277 0.79 ALDH1A1 (0.33) ALDH1A1ALOX15TSHR
SCHEMBL9187772 0.76 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL9184999 0.76 KDM4E (0.30)
SCHEMBL9190121 0.76
SCHEMBL9191418 0.74 ALDH1A1 (0.40) ALDH1A1ALOX15TSHR
SCHEMBL9585866 0.74
SCHEMBL9185625 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470434-B1 Trifluoro- resp. chlorodifluoromethoxy-1,3-5-triazine and process for their preparation BASF AG (DE) 1995-10-11 EP disclosed
US-5280118-A Trifluoro-and chlorodifluoromethoxy-1,3,5-triazines BASF AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
US-5194610-A TRIFLUORO- AND CHLORODIFLUOROMETHOXY-1,3,5-TRIAZINES AND THE PREPARATION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed
EP-0470434-A2 Trifluoro- resp. chlorodifluoromethoxy-1,3-5-triazine and process for their preparation BASF Aktiengesellschaft (DE) 1992-02-12 EP disclosed