Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 12/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2459632 | 0.91 | CA12 (0.30) | — | |
| SCHEMBL2460476 | 0.85 | FDPS (0.49) | FDPSGGPS1PDE3A | |
| SCHEMBL2459061 | 0.82 | BTN3A1 (0.40) | FDPSGGPS1PDE3A | |
| SCHEMBL2453742 | 0.76 | FDPS (0.41) | FDPSGGPS1PDE3A | |
| SCHEMBL2453750 | 0.73 | BTN3A1 (0.40) | — | |
| SCHEMBL4800069 | 0.72 | FDPS (0.57) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL14644616 | 0.66 | FDPS (0.62) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL20458106 | 0.66 | FDPS (0.62) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL12967961 | 0.66 | FDPS (0.62) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL2456971 | 0.66 | FDPS (0.51) | FDPSGGPS1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416689-B1 | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors | MERCK & CO INC (US) | 1995-11-29 | — | — | EP | claimed |