Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.53 |
| ▸ | ACP1 | P24666 | 4/20 | 0.44 |
| ▸ | CDC25B | P30305 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14194488 | 0.81 | PTPN1 (0.52) | PTPN1ACP1CDC25BALDH1A1HTT | |
| SCHEMBL70825 | 0.72 | PTPN1 (0.56) | PTPN1ACP1CDC25BALDH1A1HTT | |
| SCHEMBL13403500 | 0.70 | PTPN1 (0.59) | PTPN1ACP1CDC25BALDH1A1HTT | |
| SCHEMBL1356857 | 0.70 | PTPN1 (0.62) | PTPN1ACP1CDC25BALDH1A1HTT | |
| SCHEMBL14194487 | 0.68 | PTPN1 (0.57) | PTPN1ACP1CDC25BALDH1A1HTT | |
| SCHEMBL17748526 | 0.68 | PTPN1 (0.56) | PTPN1ACP1CDC25BALDH1A1HTT | |
| SCHEMBL14194482 | 0.68 | PTPN1 (0.68) | PTPN1ACP1CDC25BALDH1A1HTT | |
| SCHEMBL17481385 | 0.68 | PTPN1 (0.52) | PTPN1ACP1CDC25BALDH1A1HTT | |
| SCHEMBL20351495 | 0.68 | PTPN1 (0.56) | PTPN1ACP1CDC25BALDH1A1HTT | |
| SCHEMBL20826561 | 0.67 | PTPN1 (0.86) | PTPN1ACP1CDC25BALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678794-B2 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY (US) | 2010-03-16 | — | — | US | disclosed |
| US-20080004321-A1 | 3-{[4-(4-acetyl-3-hydroxy-2-propylphenoxymethyl)-phenyl]-(S)-hydroxymethyl}-benzoic acid; anxiolytic, neuroleptic agent and antidepressant as glutamate receptor agonist; antiinflammatory agent as leukotriene receptor agonist; | ELI LILLY AND COMPANY | 2008-01-03 | — | — | US | disclosed |
| EP-0456073-B1 | Multifunctional compounds having alpha-diazo-beta-ketoester units and sulfonic acid ester units and process for their preparation. | HOECHST AG (DE) | 1995-10-25 | — | — | EP | disclosed |
| US-5191069-A | Photosensitive compounds with heat resistance | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0456073-A2 | Multifunctional compounds having alpha-diazo-beta-ketoester units and sulfonic acid ester units and process for their preparation. | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004321-A1 | 3-{[4-(4-acetyl-3-hydroxy-2-propylphenoxymethyl)-phenyl]-(S)-hydroxymethyl}-benzoic acid; anxiolytic, neuroleptic agent and antidepressant as glutamate receptor agonist; antiinflammatory agent as leukotriene receptor agonist; | LTB4R, LTB4R2, CYSLTR1 | PTPN1 4339/4885ACP1 3093/4885CDC25B 4167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.