Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620086 | 0.88 | KDM4E (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11233656 | 0.88 | KDM4E (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11236764 | 0.83 | KDM4E (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11237184 | 0.81 | HTT (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| Sulfuric Acid SCHEMBL9190041 | 0.81 | PPARG (0.36) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4253904 | 0.80 | NPC1 (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11542384 | 0.80 | NPC1 (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11541708 | 0.78 | NPC1 (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| Octrizole SCHEMBL29349945 | 0.78 | NPC1 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| Octrizole SCHEMBL28983126 | 0.78 | NPC1 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466491-A | Polymer substrate with curable coating and gelation inhibitor sensitive to radiation | GENERAL ELECTRIC COMPANY (US) | 1995-11-14 | — | — | US | disclosed |