Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233656 | 0.93 | KDM4E (0.39) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11237184 | 0.90 | HTT (0.40) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11236765 | 0.87 | KDM4E (0.43) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11238393 | 0.84 | NPC1 (0.59) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| Benzene SCHEMBL9190034 | 0.83 | NPC1 (0.41) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1620086 | 0.82 | KDM4E (0.39) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11234227 | 0.80 | NPC1 (0.59) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11233663 | 0.80 | CNR1 (0.39) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11237186 | 0.78 | CNR2 (0.40) | KDM4ESMN1; SMN2POLBTDP1L3MBTL1 | |
| SCHEMBL18375145 | 0.76 | POLB (0.46) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344830-A | WEATHERPROOFING | GENERAL ELECTRIC COMPANY (US) | 1982-08-17 | — | — | US | disclosed |