SCHEMBL9190050

SCHEMBL9190050

CCc1cccc(CC)c1SSc1c(CC)cccc1CC

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.52
GABRB2 P47870 4/20 0.52
MGLL Q99685 1/20 0.37
PDK2 Q15119 1/20 0.36
KCNH2 Q12809 2/20 0.35
SCN5A Q14524 2/20 0.35
TP53 P04637 2/20 0.35
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
DAO P14920 2/20 0.34
HTR1A P08908 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
CACNA1C Q13936 1/20 0.34
CLCN2 P51788 1/20 0.33
DDO Q99489 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193727 0.89 GABRA1 (0.43) GABRA1GABRB2TP53TAAR1
SCHEMBL9190422 0.87 HPGD (0.50) GABRA1GABRB2MGLLKCNH2TP53
SCHEMBL9195152 0.87 APOBEC3G (0.48) GABRA1GABRB2MGLLMAPTNPSR1
SCHEMBL9269383 0.85 GABRA1 (0.44) GABRA1GABRB2TP53TAAR1
SCHEMBL9805899 0.84 GABRA1 (0.43) GABRA1GABRB2L3MBTL1TAAR1
SCHEMBL9193804 0.83 GABRA1 (0.52) GABRA1GABRB2MGLLPDK2KCNH2
SCHEMBL9190039 0.82 APOBEC3G (0.39) GABRA1GABRB2MAPTL3MBTL1TAAR1
SCHEMBL9190189 0.82 GABRA1 (0.38) GABRA1GABRB2MAPT
SCHEMBL914993 0.74 PDK2 (0.38) GABRA1GABRB2PDK2MAPTNPSR1
SCHEMBL9193497 0.74 GABRA1 (0.32) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63241032-A None JP disclosed
EP-4361200-A1 METHOD FOR MANUFACTURING SULFUR-CONTAINING POLYMER Nippon Shokubai Co., Ltd. (JP) 2024-05-01 EP disclosed
EP-0402481-B1 PRODUCTION OF POLYARYLENE THIOETHER PROD DEV RES INST (JP) 1995-10-25 EP disclosed
US-5290911-A Forming polymers by catalytic oxidative coupling RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1994-03-01 US disclosed
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US disclosed
US-4983720-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-01-08 US disclosed
EP-0402481-A1 PRODUCTION OF POLYARYLENE THIOETHER RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1990-12-19 EP disclosed
US-4931542-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) 1990-06-05 US disclosed
JP-S63241032-A PRODUCTION OF POLYARYLENE THIOETHER TSUCHIDA HIDETOSHI 1988-10-06 JP disclosed
EP-0281036-A2 A process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-09-07 EP disclosed