Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 9/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172179 | 1.00 | KDM4E (0.59) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| SCHEMBL2838848 | 1.00 | KDM4E (0.59) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| SCHEMBL12418041 | 1.00 | KDM4E (0.59) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| SCHEMBL4272229 | 1.00 | KDM4E (0.59) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| SCHEMBL837417 | 1.00 | KDM4E (0.59) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| Hydrochloric Acid SCHEMBL5174621 | 0.98 | ALDH1A1 (0.61) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| Hydrochloric Acid SCHEMBL837391 | 0.98 | ALDH1A1 (0.61) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| SCHEMBL851371 | 0.83 | AOC3 (0.62) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| SCHEMBL8135905 | 0.83 | AOC3 (0.62) | KDM4ELMNAADRA2AADRA2CHIF1A | |
| SCHEMBL8028471 | 0.82 | AOC3 (0.49) | KDM4ELMNAADRA2AADRA2CHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534553-B1 | Method for the preparation of an alpha-amino alcohol | DSM NV (NL) | 1995-09-27 | — | — | EP | disclosed |
| US-5276190-A | Method for the preparation of an alcohol | DSM N.V. (NL) | 1994-01-04 | — | — | US | disclosed |
| EP-0534553-A1 | Method for the preparation of an alpha-amino alcohol | DSM N.V. (NL) | 1993-03-31 | — | — | EP | disclosed |