Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194110 | 0.84 | MAPT (0.42) | MAPTMEN1CYP1A2TSHRKMT2A | |
| SCHEMBL5722854 | 0.82 | MAPT (0.59) | MAPTPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9189660 | 0.81 | IGF1R (0.41) | MAPTMEN1CYP1A2TSHRKMT2A | |
| SCHEMBL1559782 | 0.79 | MAPT (0.43) | MAPTMEN1CYP1A2KMT2APTGER1 | |
| SCHEMBL8465903 | 0.76 | MAPT (0.70) | MAPTCYP1A2PTGER1PTGER4PTGER3 | |
| SCHEMBL5198640 | 0.76 | MEN1 (0.54) | MAPTMEN1CYP1A2TSHRKMT2A | |
| SCHEMBL1559732 | 0.75 | MAPT (0.43) | MAPTMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL5200187 | 0.75 | MEN1 (0.51) | MAPTMEN1CYP1A2TSHRKMT2A | |
| SCHEMBL22973045 | 0.73 | MAPT (0.52) | MAPTL3MBTL1SMN1; SMN2TDP1HTR1A | |
| SCHEMBL5200408 | 0.72 | MAPT (0.51) | MAPTMEN1CYP1A2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682662-A1 | BICYCLIC CARBOXYLIC ACID LEUKOTRIENE B 4? ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-11-22 | — | — | EP | disclosed |
| WO-1995015956-A1 | BICYCLIC CARBOXYLIC ACID LEUKOTRIENE B4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-15 | — | — | WO | disclosed |