Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 6/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603875 | 0.82 | — | — | |
| SCHEMBL432483 | 0.78 | — | — | |
| SCHEMBL374192 | 0.78 | — | — | |
| SCHEMBL35509 | 0.78 | — | — | |
| SCHEMBL23621134 | 0.75 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9MAOAMAOB | |
| SCHEMBL9301611 | 0.75 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9MAOAMAOB | |
| SCHEMBL20582013 | 0.75 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9MAOAMAOB | |
| SCHEMBL22001696 | 0.75 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9MAOAMAOB | |
| SCHEMBL804333 | 0.75 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9MAOAMAOB | |
| Water SCHEMBL7174460 | 0.75 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021658-A1 | Polyketal Compounds, Synthesis, and Applications | SEGETIS, INC. (US) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021658-A1 | Polyketal Compounds, Synthesis, and Applications | TKT, KYAT1, KHK | SMN1; SMN2 4416/4885CA1 1779/4885CA9 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.