Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | SHBG | P04278 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.61 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 6/20 | 0.58 |
| ▸ | FNTB | P49356 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381224 | 1.00 | SERPINA6 (0.61) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL9267304 | 0.89 | HSD17B10 (0.63) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL11845368 | 0.89 | HSD17B10 (0.71) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL9267319 | 0.89 | HSD17B10 (0.63) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL11845386 | 0.89 | HSD17B10 (0.71) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL11852315 | 0.89 | HSD17B10 (0.71) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL9193185 | 0.87 | FNTA (0.73) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL9193196 | 0.87 | FNTA (0.73) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL10868078 | 0.84 | SERPINA6 (0.80) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 | |
| SCHEMBL9221947 | 0.84 | SERPINA6 (0.80) | SERPINA6LMNAHSD17B10NR3C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431151-B1 | METHOD FOR PREPARING 21-BROM-4-PREGNEN-3,20-DIONE DERIVATIVES | SCHERING AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| WO-1990013558-A1 | METHOD FOR PREPARING 21-BROM-4-PREGNEN-3,20-DIONE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-11-15 | — | — | WO | disclosed |