Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.71 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | SHBG | P04278 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.71 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.71 |
| ▸ | FNTA | P49354 | 5/20 | 0.58 |
| ▸ | FNTB | P49356 | 5/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845386 | 1.00 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1TSHRLMNA | |
| SCHEMBL11845368 | 1.00 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1TSHRLMNA | |
| SCHEMBL9267304 | 0.92 | HSD17B10 (0.63) | HSD17B10SERPINA6NR3C1TSHRLMNA | |
| SCHEMBL9267319 | 0.92 | HSD17B10 (0.63) | HSD17B10SERPINA6NR3C1TSHRLMNA | |
| SCHEMBL11796127 | 0.90 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1TSHRLMNA | |
| SCHEMBL10381224 | 0.89 | SERPINA6 (0.61) | HSD17B10SERPINA6NR3C1TSHRLMNA | |
| SCHEMBL9191538 | 0.89 | SERPINA6 (0.61) | HSD17B10SERPINA6NR3C1TSHRLMNA | |
| SCHEMBL10079789 | 0.89 | HSD17B10 (0.69) | HSD17B10SERPINA6NR3C1TSHRLMNA | |
| SCHEMBL9193185 | 0.88 | FNTA (0.73) | HSD17B10SERPINA6NR3C1TSHRLMNA | |
| SCHEMBL9193196 | 0.88 | FNTA (0.73) | HSD17B10SERPINA6NR3C1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984544-A | Retinoic acid esters of steroids of the pregnane series, their use in the treatment of acne and pharmaceutical formulations useful therefor | SCHERING CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |