SCHEMBL9192080

SCHEMBL9192080

C=CC(C)=CC(C=Cc1ccccc1)=C(C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 4/20 0.44
LMNA P02545 3/20 0.44
MAPT P10636 3/20 0.44
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
PLIN1 O60240 2/20 0.44
RECQL P46063 2/20 0.44
PLIN5 Q00G26 2/20 0.44
ABHD5 Q8WTS1 2/20 0.44
TNKS O95271 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4250758 0.84 TDP1 (0.64) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL8862854 0.82 GLA (0.44) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL9472622 0.81 GLA (0.43) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL5161450 0.80 GLA (0.51) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL269366 0.80 TDP1 (0.51) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL321987 0.79 GLA (0.50) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL5608702 0.76 GLA (0.48) GLATDP1ALDH1A1LMNAMAPT
Acrylonitrile SCHEMBL22656767 0.73 GLA (0.44) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL3127156 0.73 TDP1 (0.64) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL221211 0.73 TDP1 (0.64) GLATDP1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5422225-A Block polymer includes acrylic monomer block containing acid groups SHELL OIL COMPANY (US) 1995-06-06 US disclosed