SCHEMBL321987

SCHEMBL321987

C=CC(C)=CC(C)=C(C=Cc1ccccc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 4/20 0.44
LMNA P02545 3/20 0.44
MAPT P10636 3/20 0.44
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
PLIN1 O60240 2/20 0.44
RECQL P46063 2/20 0.44
PLIN5 Q00G26 2/20 0.44
ABHD5 Q8WTS1 2/20 0.44
TNKS O95271 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9192080 0.79 GLA (0.50) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL11119689 0.79 MAPT (0.55) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL9472622 0.78 GLA (0.43) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL589902 0.77 GLA (0.51) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL5608702 0.76 GLA (0.48) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL28514734 0.75 GLA (0.62) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL29849743 0.75 GLA (0.62) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL29849933 0.75 GLA (0.62) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL3970920 0.74 HDAC3 (0.60) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL8862854 0.73 GLA (0.44) GLATDP1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8680362-B2 Substrate coated with a hydrophilic elastomer THE PROCTER & GAMBLE COMPANY (US) 2014-03-25 US disclosed
EP-2451853-B1 SUBSTRATE COATED WITH A HYDROPHILIC ELASTOMER PROCTER & GAMBLE (US) 2013-07-24 EP disclosed
EP-2440602-B1 SUPERABSORBENT POLYMER PARTICLES COATED WITH A HYDROPHILIC ELASTOMER AND ABSORBENT ARTICLE COMPRISING SUCH PARTICLES PROCTER & GAMBLE (US) 2013-05-08 EP disclosed
US-8409664-B2 Superabsorbent polymer particles coated with a hydrophilic elastomer and absorbent article comprising such particles THE PROCTER & GAMBLE COMPANY (US) 2013-04-02 US disclosed
EP-2451853-A1 SUBSTRATE COATED WITH A HYDROPHILIC ELASTOMER The Procter & Gamble Company (US) 2012-05-16 EP disclosed
EP-2440602-A1 SUPERABSORBENT POLYMER PARTICLES COATED WITH A HYDROPHILIC ELASTOMER AND ABSORBENT ARTICLE COMPRISING SUCH PARTICLES The Procter & Gamble Company (US) 2012-04-18 EP disclosed
WO-2012006058-A1 SUPERABSORBENT POLYMER PARTICLES COATED WITH A HYDROPHILIC ELASTOMER AND ABSORBENT ARTICLE COMPRISING SUCH PARTICLES THE PROCTER & GAMBLE COMPANY (US) 2012-01-12 WO disclosed
WO-2012006057-A1 SUBSTRATE COATED WITH A HYDROPHILIC ELASTOMER THE PROCTER & GAMBLE COMPANY (US) 2012-01-12 WO disclosed
US-20110319847-A1 Superabsorbent Polymer Particles Coated With A Hydrophilic Elastomer And Absorbent Article Comprising Such Particles PROCTER & GAMBLE COMPANY, THE 2011-12-29 US disclosed
US-20110319848-A1 Substrate Coated With A Hydrophilic Elastomer PROCTER & GAMBLE COMPANY, THE 2011-12-29 US disclosed