SCHEMBL9192425

SCHEMBL9192425

Cc1cccc(N(c2cc(C)cc(C)c2)C2(N(c3cccc(C)c3)c3cc(C)cc(C)c3)C=CC(c3ccccc3)=CC2)c1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188139 0.95 HSD17B1 (0.32) HSD17B1HSD17B2
SCHEMBL710237 0.95 HSD17B1 (0.32) HSD17B1HSD17B2
SCHEMBL29569369 0.95 HSD17B1 (0.32) HSD17B1HSD17B2
SCHEMBL29958416 0.95 HSD17B1 (0.32) HSD17B1HSD17B2
SCHEMBL9190418 0.94
SCHEMBL6761167 0.89 HSD17B1 (0.30) HSD17B1HSD17B2
SCHEMBL31748685 0.88 TP53 (0.30)
SCHEMBL16469637 0.88 TP53 (0.30)
SCHEMBL31124412 0.88 TP53 (0.30)
SCHEMBL15514367 0.88 TP53 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0390196-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-09-20 EP disclosed
EP-0385440-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-05-03 EP disclosed
US-5153088-A High sensitivity mixture also with charge transferring substituted phenyl diamines MITA INDUSTRIAL CO., LTD. (JP) 1992-10-06 US disclosed
US-5059503-A Used for copying machine MITA INDUSTRIAL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0390196-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed
EP-0385440-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-09-05 EP disclosed