SCHEMBL9192513

SCHEMBL9192513

COc1cc(CC2C(=O)OC(C)(C)OC2=O)ccc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 2/20 0.62
NPSR1 Q6W5P4 1/20 0.62
SHBG P04278 3/20 0.56
GAA P10253 2/20 0.54
CYP3A4 P08684 4/20 0.53
MAPK1 P28482 2/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
MAP2K1 Q02750 1/20 0.53
ALOX5 P09917 2/20 0.48
OR51E2 Q9H255 1/20 0.48
ALDH1A1 P00352 3/20 0.48
TSHR P16473 2/20 0.48
NFKB1 P19838 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TAAR1 Q96RJ0 2/20 0.47
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30595402 1.00 GLA (0.62) GLANPSR1SHBGGAACYP3A4
SCHEMBL30595403 1.00 GLA (0.62) GLANPSR1SHBGGAACYP3A4
SCHEMBL30595404 1.00 GLA (0.62) GLANPSR1SHBGGAACYP3A4
SCHEMBL3092054 0.87 GLA (0.67) GLANPSR1CYP3A4MAPK1NPC1
SCHEMBL9201096 0.83 GLA (0.60) GLANPSR1CYP3A4MAPK1CYP1A2
SCHEMBL30020294 0.78 SHBG (0.52) GLASHBGGAACYP3A4MAPK1
SCHEMBL20047913 0.78 SHBG (0.52) GLASHBGGAACYP3A4MAPK1
SCHEMBL3100458 0.77 NPSR1 (0.56) GLANPSR1GAACYP1A2CYP2C19
SCHEMBL15569868 0.77 NPSR1 (1.00) GLANPSR1ALDH1A1MEN1MAPT
SCHEMBL23388485 0.76 GAA (0.57) GAAALOX5ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116675668-A Molecular probe based on vanillin modification and preparation method and application thereof 井冈山大学 2023-09-01 CN disclosed
EP-0578849-B1 Process for the preparation of 1,3-dioxane-4,6-dione derivates BIOGAL GYOGYSZERGYAR (HU) 1995-05-17 EP disclosed
EP-0578849-A1 Process for the preparation of 1,3-dioxane-4,6-dione derivates BIOGAL GYOGYSZERGYAR (HU) 1994-01-19 EP disclosed