Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.48 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 8/20 | 0.42 |
| ▸ | CA2 | P00918 | 8/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195262 | 0.93 | MALT1 (0.52) | STK17BSTK17AMETAP2MALT1CA1 | |
| SCHEMBL9528225 | 0.85 | MALT1 (0.46) | STK17BSTK17AMALT1CA1CA2 | |
| SCHEMBL9200110 | 0.85 | MALT1 (0.48) | STK17BSTK17AMETAP2MALT1CA1 | |
| SCHEMBL9528234 | 0.84 | MALT1 (0.44) | STK17BSTK17AMETAP2MALT1CA1 | |
| SCHEMBL7766945 | 0.81 | ECE1 (0.53) | STK17BSTK17AMALT1CA1CA2 | |
| SCHEMBL12658894 | 0.81 | MALT1 (0.53) | METAP2MALT1CA1CA2CA12 | |
| SCHEMBL9197731 | 0.78 | MALT1 (0.40) | MALT1CA1CA2CA12CA9 | |
| SCHEMBL12658883 | 0.77 | MALT1 (0.54) | METAP2MALT1CA1CA2CA12 | |
| Trifluoroacetic Acid SCHEMBL7772559 | 0.76 | ECE1 (0.50) | METAP2MALT1CA1CA2CA12 | |
| Maleic Acid SCHEMBL7772576 | 0.76 | ECE1 (0.63) | METAP2MALT1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574433-B1 | 6,9-BIS(AMINO SUBSTITUTED)BENZO g]PHTHALAZINE-5,10-DIONES AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-05-31 | — | — | EP | disclosed |
| WO-1992015307-A1 | 6,9-BIS(AMINO SUBSTITUTED)BENZO[g]PHTHALAZINE-5,10-DIONES AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-09-17 | — | — | WO | disclosed |