Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | LATS1 | O95835 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192525 | 0.93 | STK17B (0.48) | MALT1DDB1CRBNCA12CA1 | |
| SCHEMBL9528225 | 0.92 | MALT1 (0.46) | MALT1DDB1CRBNBCHEPDE3B | |
| SCHEMBL9200110 | 0.92 | MALT1 (0.48) | MALT1DDB1CRBNBCHEPDE3B | |
| SCHEMBL9528234 | 0.90 | MALT1 (0.44) | MALT1DDB1CRBNBCHEPDE3B | |
| SCHEMBL7766945 | 0.88 | ECE1 (0.53) | MALT1DDB1CRBNBCHEPDE3B | |
| SCHEMBL9197731 | 0.84 | MALT1 (0.40) | MALT1DDB1CRBNBCHEPDE3B | |
| Maleic Acid SCHEMBL7772576 | 0.83 | ECE1 (0.63) | MALT1DDB1CRBNBCHEPDE3B | |
| Trifluoroacetic Acid SCHEMBL7772559 | 0.83 | ECE1 (0.50) | MALT1DDB1CRBNBCHEPDE3B | |
| SCHEMBL9197474 | 0.79 | KMT2A (0.43) | CA12CA9MEN1NSD2POLB | |
| SCHEMBL18086441 | 0.77 | MALT1 (0.55) | MALT1DDB1CRBNBCHECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574433-B1 | 6,9-BIS(AMINO SUBSTITUTED)BENZO g]PHTHALAZINE-5,10-DIONES AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-05-31 | — | — | EP | disclosed |
| EP-0574433-A1 | 6,9-BIS(AMINO SUBSTITUTED)BENZO g]PHTHALAZINE-5,10-DIONES AS ANTITUMOR AGENTS. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992015307-A1 | 6,9-BIS(AMINO SUBSTITUTED)BENZO[g]PHTHALAZINE-5,10-DIONES AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-09-17 | — | — | WO | disclosed |