Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 6/20 | 0.33 |
| ▸ | NCF1 | P14598 | 2/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764334 | 0.82 | KDM4E (0.49) | KDM4ELMNACYP3A4TSHRTP53 | |
| SCHEMBL9764204 | 0.79 | LMNA (0.39) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL321696 | 0.78 | CYP1A2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Iodide SCHEMBL27088326 | 0.76 | CYP1A2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Bromide SCHEMBL28155749 | 0.76 | CYP1A2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL28290080 | 0.76 | KCNH2 (0.43) | KDM4ELMNACYP3A4TSHRTDP1 | |
| SCHEMBL3696387 | 0.76 | KCNH2 (0.43) | KDM4ELMNACYP3A4TSHRTDP1 | |
| SCHEMBL28167678 | 0.76 | KCNH2 (0.43) | KDM4ELMNACYP3A4TSHRTDP1 | |
| Bromide SCHEMBL30568709 | 0.75 | KCNH2 (0.42) | KDM4ELMNACYP3A4TSHRTDP1 | |
| Bromide SCHEMBL28288622 | 0.75 | KCNH2 (0.42) | KDM4ELMNACYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538789-B1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from vinyl compounds containing heterocyclic nitrogen groups | BRIDGESTONE CORP (JP) | 1995-12-13 | — | — | EP | disclosed |
| EP-0538789-A1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from vinyl compounds containing heterocyclic nitrogen groups | BRIDGESTONE CORPORATION (JP) | 1993-04-28 | — | — | EP | disclosed |