⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9191974 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL9194367 | 0.95 | — | — | |
| SCHEMBL29818845 | 0.94 | TSHR (1.00) | — | |
| SCHEMBL1938 | 0.94 | — | — | |
| SCHEMBL7249115 | 0.89 | — | — | |
| SCHEMBL8377677 | 0.89 | — | — | |
| SCHEMBL3422882 | 0.89 | TSHR (0.89) | — | |
| SCHEMBL6123214 | 0.89 | — | — | |
| SCHEMBL8379533 | 0.89 | — | — | |
| SCHEMBL8378123 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533003-B1 | Process for the preparation of fluorine containing derivatives | SOLVAY FLUOR & DERIVATE (DE) | 1995-12-06 | — | — | EP | claimed |
| US-5336817-A | Method of preparing 1,1,1,2-tetrafluoroethane | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 1994-08-09 | — | — | US | claimed |
| US-5227546-A | Tantalum or niobium fluorosulfonate catalysts | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 1993-07-13 | — | — | US | claimed |
| JP-5238969-A | — | — | None | — | — | JP | disclosed |
| US-5336817-A | Method of preparing 1,1,1,2-tetrafluoroethane | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 1994-08-09 | — | — | US | disclosed |
| US-5283381-A | Using halogenation catalyst of (tantalum or niobium) fluorosulfonate | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 1994-02-01 | — | — | US | disclosed |
| US-5283381-A | Using halogenation catalyst of (tantalum or niobium) fluorosulfonate | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 1994-02-01 | — | — | US | disclosed |
| JP-H05238969-A | PREPARATION OF FLUORINE-CONTAINING ETHANE DERIVATIVE AND CATALYST AND FORMULATION FOR THE SAME | SOLVAY FLUOR & DERIVATE GMBH | 1993-09-17 | — | — | JP | disclosed |
| US-5227546-A | Tantalum or niobium fluorosulfonate catalysts | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5227546-A | Tantalum or niobium fluorosulfonate catalysts | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 1993-07-13 | — | — | US | disclosed |
| EP-0533003-A2 | Process for the preparation of fluorine containing derivatives | Solvay Fluor und Derivate GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |