SCHEMBL9192996

SCHEMBL9192996

CN1C(=C2SC(=S)N(CC(=O)O)C2=O)Oc2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APEX1 P27695 4/20 0.57
▸ PTGES O14684 1/20 0.57
▸ MAPT P10636 7/20 0.48
▸ MEN1 O00255 6/20 0.48
▸ KMT2A Q03164 6/20 0.48
▸ POLB P06746 3/20 0.48
▸ CTDSP1 Q9GZU7 2/20 0.48
▸ USP2 O75604 1/20 0.48
▸ THRB P10828 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ RECQL P46063 1/20 0.48
▸ BLM P54132 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ DUSP3 P51452 1/20 0.47
▸ MCL1 Q07820 1/20 0.47
▸ ALDH1A1 P00352 3/20 0.44
▸ LMNA P02545 2/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ NPC1 O15118 2/20 0.44
▸ AKR1B1 P15121 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9192992 1.00 APEX1 (0.57) APEX1PTGESMAPTMEN1KMT2A
SCHEMBL2340187 0.85 MEN1 (0.55) MAPTMEN1KMT2APOLBCTDSP1
SCHEMBL2340185 0.85 MEN1 (0.55) MAPTMEN1KMT2APOLBCTDSP1
SCHEMBL13531851 0.79 MEN1 (0.48) APEX1PTGESMAPTMEN1KMT2A
SCHEMBL8606929 0.77 MEN1 (0.61) APEX1PTGESMAPTMEN1KMT2A
SCHEMBL8606927 0.77 MEN1 (0.61) APEX1PTGESMAPTMEN1KMT2A
SCHEMBL14220089 0.76 MEN1 (0.45) APEX1PTGESMAPTMEN1KMT2A
SCHEMBL10623018 0.76 MEN1 (0.57) MAPTMEN1KMT2APOLBTHRB
SCHEMBL10036075 0.76 MEN1 (0.57) MAPTMEN1KMT2APOLBTHRB
SCHEMBL10623015 0.76 MEN1 (0.57) MAPTMEN1KMT2APOLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333435-B1 High contrast photographic element and emulsion and process for their use EASTMAN KODAK CO (US) 1995-12-13 — — EP disclosed
EP-0345025-B1 High contrast photographic recording material and emulsion and process for their development EASTMAN KODAK CO (US) 1994-03-09 — — EP disclosed
US-5126227-A High speed, low fogging, quality, efficiency EASTMAN KODAK COMPANY (US) 1992-06-30 — — US disclosed
US-5104769-A Negative working silver halide and arylhydrazide nucleating agent EASTMAN KODAK COMPANY (US) 1992-04-14 — — US disclosed
US-5041355-A High contrast photographic element including an aryl sulfonamidophenyl hydrazide containing ethyleneoxy groups EASTMAN KODAK COMPANY (US) 1991-08-20 — — US disclosed
US-4994365-A Nucleating agents EASTMAN KODAK COMPANY (US) 1991-02-19 — — US disclosed
US-4988604-A Silver halide elements for development with alkaline agent, multilayer, nucleation agent EASTMAN KODAK COMPANY (US) 1991-01-29 — — US disclosed
US-4975354-A Silver halide developed in presence of a hydrazone using an aqueous alkaline solution; black and white photography; lithography EASTMAN KODAK COMPANY (US) 1990-12-04 — — US disclosed
EP-0209011-B1 HIGH CONTRAST PHOTOGRAPHIC ELEMENTS EXHIBITING STABILIZED SENSITIVITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-11-07 — — EP disclosed
EP-0209012-B1 HIGH CONTRAST PHOTOGRAPHIC ELEMENTS EXHIBITING REDUCED PEPPER FOG EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-11-07 — — EP disclosed
US-4912016-A Aromatic hydrazide EASTMAN KODAK COMPANY (US) 1990-03-27 — — US disclosed
EP-0345025-A1 High contrast photographic recording material and emulsion and process for their development EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-12-06 — — EP disclosed
EP-0333435-A2 High contrast photographic element and emulsion and process for their use EASTMAN KODAK COMPANY (US) 1989-09-20 — — EP disclosed
US-4650746-A HYDRAZIDE NUCLEATING AGENTS EASTMAN KODAK COMPANY (US) 1987-03-17 — — US disclosed
US-4618574-A AN ARYLHYDRAZIDE, A POLHYDROXYBENZENE AND A CARBOXYALKYL3H-THIAZOLINE-2-THIONE EASTMAN KODAK COMPANY (US) 1986-10-21 — — US disclosed
US-4560638-A Halftone imaging silver halide emulsions, photographic elements, and processes which employ novel arylhydrazides EASTMAN KODAK COMPANY (US) 1985-12-24 — — US disclosed
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