Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158190 | 0.89 | CLK1 (0.39) | CLK1GRM5HTR7NCEH1PKM | |
| SCHEMBL9865275 | 0.86 | CLK1 (0.38) | CLK1GRM5HTR7NCEH1PKM | |
| SCHEMBL9158184 | 0.86 | CLK1 (0.38) | CLK1GRM5HTR7NCEH1PKM | |
| SCHEMBL8734918 | 0.86 | CLK1 (0.38) | CLK1GRM5HTR7NCEH1PKM | |
| SCHEMBL9191662 | 0.78 | CNR1 (0.45) | — | |
| SCHEMBL9550193 | 0.78 | CNR1 (0.45) | — | |
| SCHEMBL9030991 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HPGD | |
| SCHEMBL9469921 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HPGD | |
| SCHEMBL17804225 | 0.73 | CLK1 (0.40) | CLK1GRM5HTR7NCEH1PKM | |
| SCHEMBL1400663 | 0.73 | CLK1 (0.40) | CLK1GRM5HTR7NCEH1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471262-B1 | Process for the production of substituted 3-amino-acrylesters | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| US-5196541-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-AMINOACRYLIC ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0471262-A1 | Process for the production of substituted 3-amino-acrylesters | BAYER AG (DE) | 1992-02-19 | — | — | EP | disclosed |