⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL922272 | 0.93 | ALDH1A1 (0.56) | — | |
| SCHEMBL920064 | 0.91 | ALDH1A1 (0.59) | — | |
| SCHEMBL921432 | 0.91 | ALDH1A1 (0.59) | — | |
| SCHEMBL467449 | 0.86 | — | — | |
| SCHEMBL7094868 | 0.85 | ALDH1A1 (0.67) | — | |
| SCHEMBL11060991 | 0.85 | ALDH1A1 (0.61) | — | |
| SCHEMBL7093157 | 0.83 | ALDH1A1 (0.70) | — | |
| SCHEMBL25232764 | 0.82 | — | — | |
| SCHEMBL5726618 | 0.82 | — | — | |
| SCHEMBL24478868 | 0.80 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141852-A1 | CDK2 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 益方生物科技(上海)股份有限公司 | 2023-08-03 | — | — | WO | disclosed |
| EP-3169671-A1 | SUBSTITUTED UREA DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016008433-A1 | SUBSTITUTED UREA DERIVATIVES AND PHARMACEUTICAL USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-01-21 | — | — | WO | disclosed |
| WO-2015043492-A1 | SUBSTITUTED UREA DERIVATIVES AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-04-02 | — | — | WO | disclosed |
| US-8653269-B2 | Process for preparation of t-butoxycarbonylamine compounds | NIPPON SODA CO., LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| EP-2546235-A1 | PROCESS FOR PREPARATION OF t-BUTOXYCARBONYLAMINE COMPOUNDS | Nippon Soda Co., Ltd. (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20130005981-A1 | PROCESS FOR PREPARATION OF t-BUTOXYCARBONYLAMINE COMPOUNDS | NIPPON SODA CO., LTD. (JP) | 2013-01-03 | — | — | US | disclosed |
| US-8163770-B2 | Benzoxathiin derivative | MSD. K. K. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2345328-A1 | COMPOSITION FOR AGRICULTURAL USE | Sumitomo Chemical Company, Limited (JP) | 2011-07-20 | — | — | EP | disclosed |
| EP-0936216-A1 | NOVEL ACETAMIDE DERIVATIVES AND PROTEASE INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998038199-A1 | NOVEL ERYTHROMYCIN DERIVATIVES, METHOD OF PREPARATION AND APPLICATION AS MEDICINES | HOECHST MARION ROUSSEL (FR) | 1998-09-03 | — | — | WO | disclosed |
| US-5770579-A | Erythromycin compounds | ROUSSEL UCLAF (FR) | 1998-06-23 | — | — | US | disclosed |
| US-5561118-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1996-10-01 | — | — | US | disclosed |
| EP-0487411-B1 | Erythromycin derivatives, their preparation, intermediates obtained and their application as medicaments | ROUSSEL UCLAF (FR) | 1996-01-31 | — | — | EP | disclosed |
| US-5444051-A | BACTERICIDES | ROUSSEL UCLAF (FR) | 1995-08-22 | — | — | US | disclosed |
| EP-0487411-A1 | Erythromycin derivatives, their preparation, intermediates obtained and their application as medicaments | ROUSSEL UCLAF (FR) | 1992-05-27 | — | — | EP | disclosed |
| EP-0033255-B1 | OXIMES DERIVED FROM ERYTHROMYCIN A, THEIR PREPARATION, THEIR APPLICATION IN PHARMACEUTICALS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1984-08-29 | — | — | EP | disclosed |
| US-4349545-A | Novel erythromycin a derivatives | ROUSSEL UCLAF (FR) | 1982-09-14 | — | — | US | disclosed |
| EP-0033255-A1 | Oximes derived from erythromycin A, their preparation, their application in pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1981-08-05 | — | — | EP | disclosed |