SCHEMBL9194352

SCHEMBL9194352

O=C(/C=C/C=C/C1(F)CC1c1ccc(Br)c(Br)c1)Nc1ccccc1CF

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9196128 0.89 EGFR (0.42) EGFR
SCHEMBL9190860 0.87 MMP1 (0.39) EGFR
SCHEMBL27447172 0.87 MMP1 (0.39) EGFR
SCHEMBL9193683 0.87 MMP1 (0.40) EGFR
SCHEMBL9190956 0.87 MMP1 (0.40) EGFR
SCHEMBL9191694 0.87 MMP1 (0.40) EGFR
SCHEMBL9188945 0.87 MMP1 (0.40) EGFR
SCHEMBL9191690 0.87 MMP1 (0.40) EGFR
SCHEMBL9455405 0.87 MMP1 (0.40) EGFR
SCHEMBL9188292 0.84 MAOB (0.41) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524041-B1 Pesticides ROUSSEL UCLAF (FR) 1995-09-20 EP claimed
EP-0524041-B1 Pesticides ROUSSEL UCLAF (FR) 1995-09-20 EP disclosed
EP-0524041-A2 Pesticides ROUSSEL UCLAF (FR) 1993-01-20 EP disclosed