Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942593 | 0.91 | HIF1A (0.55) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A | |
| SCHEMBL9188139 | 0.90 | ALOX15 (0.66) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A | |
| SCHEMBL9193506 | 0.84 | MAPK1 (0.46) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A | |
| SCHEMBL9429990 | 0.83 | CYP2D6 (0.55) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A | |
| SCHEMBL7940340 | 0.82 | HIF1A (0.52) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A | |
| SCHEMBL6053413 | 0.81 | HIF1A (0.59) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A | |
| SCHEMBL7933627 | 0.81 | HIF1A (0.51) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A | |
| SCHEMBL9195491 | 0.80 | HSD17B10 (0.47) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A | |
| SCHEMBL7117673 | 0.80 | CYP2C19 (1.00) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A | |
| SCHEMBL9193500 | 0.79 | CNR1 (0.42) | CYP2C19CYP2D6CYP1A2CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517356-B1 | Composition and method for inhibiting corrosion and/or promoting adhesion of a metal surface | ZENECA LTD (GB) | 1995-12-06 | — | — | EP | claimed |
| US-5324347-A | 2,6-bis hydroxyalkylamino methyl phenol; corrosion resistance, adhesion promoting | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-06-28 | — | — | US | disclosed |