Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724076 | 0.83 | TSHR (0.56) | KDM4ENPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL19436594 | 0.81 | CYP1A2 (0.54) | KDM4ENPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL10443550 | 0.80 | CA12 (0.66) | KDM4ETSHRHPGDKMT2ACA12 | |
| SCHEMBL6866819 | 0.79 | TSHR (0.47) | KDM4ENPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL8086920 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1TSHRHPGDMAPT | |
| SCHEMBL9790177 | 0.78 | CA12 (0.50) | KDM4ENPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL4001314 | 0.78 | MAPT (0.49) | KDM4ENPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL9200116 | 0.75 | ALDH1A1 (0.49) | KDM4ENPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL3998969 | 0.75 | MAPT (0.51) | KDM4EALDH1A1TSHRLMNAHPGD | |
| SCHEMBL619175 | 0.74 | TSHR (0.69) | KDM4ENPSR1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639182-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |