Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196683 | 0.88 | LTB4R (0.62) | LTB4R | |
| SCHEMBL9200604 | 0.87 | LTB4R (0.62) | LTB4R | |
| SCHEMBL8734195 | 0.86 | LTB4R (0.85) | LTB4R | |
| SCHEMBL8065588 | 0.85 | LTB4R (0.98) | LTB4R | |
| SCHEMBL8073392 | 0.85 | LTB4R (0.82) | LTB4R | |
| SCHEMBL8065585 | 0.84 | LTB4R (1.00) | LTB4R | |
| SCHEMBL13696782 | 0.84 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8078498 | 0.84 | LTB4R (0.84) | LTB4R | |
| SCHEMBL7027871 | 0.83 | LTB4R (0.80) | LTB4R | |
| SCHEMBL7027874 | 0.83 | LTB4R (0.80) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639975-A1 | HETEROCYCLIC-SUBSTITUTED PYRIDINE COMPOUNDS AND USES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-01 | — | — | EP | claimed |
| EP-0639975-A4 | HETEROCYCLIC-SUBSTITUTED PYRIDINE COMPOUNDS AND USES. | SMITHKLINE BEECHAM CORP (US) | 1994-10-24 | — | — | EP | claimed |
| WO-1993010780-A1 | HETEROCYCLIC-SUBSTITUTED PYRIDINE COMPOUNDS AND USES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-10 | — | — | WO | claimed |
| EP-0639975-A1 | HETEROCYCLIC-SUBSTITUTED PYRIDINE COMPOUNDS AND USES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-01 | — | — | EP | disclosed |
| EP-0639975-A4 | HETEROCYCLIC-SUBSTITUTED PYRIDINE COMPOUNDS AND USES. | SMITHKLINE BEECHAM CORP (US) | 1994-10-24 | — | — | EP | disclosed |
| WO-1993010780-A1 | HETEROCYCLIC-SUBSTITUTED PYRIDINE COMPOUNDS AND USES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-10 | — | — | WO | disclosed |