Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406999 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL7507925 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL2004126 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL9406782 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL9406778 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL11909127 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL4204474 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL4311172 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL9218791 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL2679977 | 1.00 | LMNA (0.59) | LMNAMAPK1MAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995005159-A1 | ACYLATED HYDROXYALKANOATES AND THEIR USES | UNILEVER PLC (GB) | 1995-02-23 | — | — | WO | disclosed |
| EP-0466838-A4 | — | WISCONSIN ALUMNI RES FOUND (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0466838-A1 | NOVEL LIPID A DERIVATIVES AND USES THEREFOR | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1992-01-22 | — | — | EP | disclosed |
| WO-1991001134-A1 | NOVEL LIPID A DERIVATIVES AND USES THEREFOR | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-02-07 | — | — | WO | disclosed |