Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SFN | P31947 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203335 | 1.00 | HTT (0.53) | HTTKDM4EMRGPRX4MAPTCASP1 | |
| SCHEMBL1032879 | 0.85 | KDM4E (0.61) | HTTKDM4EMAPTTSHRTDP1 | |
| SCHEMBL692136 | 0.84 | KMT2A (0.65) | KDM4EMRGPRX4MAPTCASP1TSHR | |
| SCHEMBL9722695 | 0.84 | MRGPRX4 (0.51) | KDM4EMRGPRX4MAPTTP53CYP1A2 | |
| SCHEMBL27191874 | 0.83 | HTT (0.50) | HTTKDM4EMAPTCASP1TDP1 | |
| SCHEMBL5235490 | 0.82 | MRGPRX4 (0.50) | KDM4EMRGPRX4MAPTTP53CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL27869911 | 0.82 | KMT2A (0.62) | KDM4EMRGPRX4MAPTCASP1TSHR | |
| SCHEMBL27744360 | 0.82 | KMT2A (0.62) | KDM4EMRGPRX4MAPTCASP1TSHR | |
| Water SCHEMBL28856010 | 0.82 | KMT2A (0.62) | KDM4EMRGPRX4MAPTCASP1TSHR | |
| SCHEMBL28219396 | 0.82 | KMT2A (0.62) | KDM4EMRGPRX4MAPTCASP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | disclosed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | disclosed |