Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.75 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190336 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL29962224 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL9192842 | 0.82 | MTNR1A (0.75) | MTNR1AMTNR1B | |
| SCHEMBL8185656 | 0.81 | MTNR1A (0.73) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19911346 | 0.80 | MTNR1A (0.64) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL21315666 | 0.79 | MTNR1A (0.86) | MTNR1AMTNR1B | |
| SCHEMBL21315635 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8757514 | 0.78 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| SCHEMBL19911358 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL27038883 | 0.77 | MTNR1A (0.65) | MTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527687-B1 | Novel arylethylamin derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-11-22 | — | — | EP | disclosed |
| EP-0527687-A2 | Novel arylethylamin derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-17 | — | — | EP | disclosed |