Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192620 | 0.87 | KDM4E (0.35) | KDM4EATMCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9196255 | 0.86 | PGK1 (0.34) | CYP1A2CYP2C9LMNAALDH1A1BLM | |
| SCHEMBL29868312 | 0.81 | GAA (0.49) | KDM4EATMCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9432275 | 0.81 | GAA (0.49) | KDM4EATMCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7807011 | 0.80 | ATF1 (0.34) | CHRNA7PGK1 | |
| SCHEMBL6468496 | 0.79 | NT5E (0.42) | KDM4EATMCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9585981 | 0.78 | PTGS1 (0.37) | KDM4EATMCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7804841 | 0.78 | POLB (0.35) | KDM4EATMCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7806822 | 0.77 | HSP90AA1 (0.53) | KDM4ECYP1A2CYP2C9NPSR1LMNA | |
| SCHEMBL7925318 | 0.74 | HPGD (0.45) | KDM4EATMCYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445644-B1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| US-5237063-A | TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| EP-0445644-A1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |