Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498909 | 0.73 | KDM4E (0.45) | KDM4EMAPTALDH1A1HTTHPGD | |
| SCHEMBL29352476 | 0.73 | KDM4E (0.45) | KDM4EMAPTALDH1A1HTTHPGD | |
| SCHEMBL218043 | 0.73 | — | — | |
| SCHEMBL7289957 | 0.72 | HTR2C (0.33) | KDM4EMAPTLMNAHTR2C | |
| SCHEMBL31514293 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| Bromide SCHEMBL29671076 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29671085 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12278092 | 0.69 | KDM4E (0.42) | KDM4EMAPTALDH1A1HTTHPGD | |
| SCHEMBL20182388 | 0.69 | KDM4E (0.42) | KDM4EMAPTALDH1A1HTTHPGD | |
| SCHEMBL2368365 | 0.69 | KDM4E (0.42) | KDM4EMAPTALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487768-B1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL (JP) | 1995-01-25 | — | — | EP | claimed |
| EP-0487768-A1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-03 | — | — | EP | claimed |
| JP-6016556-A | — | — | None | — | — | JP | disclosed |
| JP-H0616556-A | SLIGHTLY SOLUBLE MEDICINE-CONTAINING PREPARATION | YOSHITOMI PHARMACEUT IND LTD | 1994-01-25 | — | — | JP | disclosed |