Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104838 | 0.81 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9191150 | 0.79 | CYP19A1 (0.65) | CYP19A1SLC1A2KCNH2CACNA1FHTR1A | |
| SCHEMBL8408606 | 0.76 | CYP19A1 (1.00) | CYP19A1 | |
| SCHEMBL8102936 | 0.74 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL2348017 | 0.72 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9194497 | 0.71 | CYP19A1 (0.54) | CYP19A1CYP11B1CYP11B2SLC1A2KCNH2 | |
| SCHEMBL8104816 | 0.71 | CYP19A1 (0.54) | CYP19A1CYP11B1CYP11B2SLC1A2KCNH2 | |
| SCHEMBL8109000 | 0.71 | CYP19A1 (0.54) | CYP19A1SLC1A2KCNH2CACNA1FHTR1A | |
| SCHEMBL8110779 | 0.70 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8104979 | 0.68 | CYP19A1 (0.72) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | claimed |
| WO-1994013645-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | Orion-Yhtymä Oy (FI) | 1994-06-23 | — | — | WO | claimed |
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994013645-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | Orion-Yhtymä Oy (FI) | 1994-06-23 | — | — | WO | disclosed |