Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.66 |
| ▸ | RELA | Q04206 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | ACR | P10323 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RARB | P10826 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962712 | 0.96 | LMNA (0.60) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL8922419 | 0.93 | NPC1 (0.55) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL8850790 | 0.91 | LMNA (0.53) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9878891 | 0.90 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9879238 | 0.90 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9879201 | 0.90 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9879041 | 0.90 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9878779 | 0.90 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9878053 | 0.90 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9878488 | 0.90 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471277-B1 | Silanol compounds, polymerizable monomers and polymers having mesogenic groups | SAGAMI CHEM RES (JP) | 1995-11-15 | — | — | EP | disclosed |
| US-5329034-A | Silanol compounds, polymerizable monomers and polymers having mesogenic groups | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0293870-B1 | METHOD FOR ELECTRIC FIELD ORIENTATION OF LIQUID CRYSTAL POLYMERS AND ORIENTED MATERIALS OF LIQUID CRYSTAL POLYMERS OBTAINED BY THE METHOD | KURARAY CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| EP-0471277-A2 | Silanol compounds, polymerizable monomers and polymers having mesogenic groups | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-02-19 | — | — | EP | disclosed |
| US-4983318-A | Method for electric field orientation of liquid crystal polymers and oriented materials of liquid crystal polymers obtained by the method | KURARAY CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0293870-A1 | Method for electric field orientation of liquid crystal polymers and oriented materials of liquid crystal polymers obtained by the method | KURARAY CO., LTD. (JP) | 1988-12-07 | — | — | EP | disclosed |
| US-4358391-A | BRANCHED POLYSILOXANES | WACKER-CHEMIE GMBH (DE) | 1982-11-09 | — | — | US | disclosed |