Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610051 | 1.00 | TSHR (0.52) | TSHRACHEGRM5ALDH1A1FFAR1 | |
| SCHEMBL1610072 | 0.81 | TRPA1 (0.39) | TSHRACHEALDH1A1FFAR1CA1 | |
| SCHEMBL1611529 | 0.75 | TSHR (0.46) | TSHRACHEGRM5ALDH1A1FFAR1 | |
| SCHEMBL1141159 | 0.73 | TSHR (0.62) | TSHRACHEGRM5ALDH1A1FFAR1 | |
| SCHEMBL3644208 | 0.73 | TSHR (0.62) | TSHRACHEGRM5ALDH1A1FFAR1 | |
| SCHEMBL30666154 | 0.73 | TSHR (0.62) | TSHRACHEGRM5ALDH1A1FFAR1 | |
| SCHEMBL19875811 | 0.73 | TSHR (0.62) | TSHRACHEGRM5ALDH1A1FFAR1 | |
| SCHEMBL3113206 | 0.72 | CYP1A2 (0.39) | TSHRACHEALDH1A1FFAR1CA1 | |
| SCHEMBL1609399 | 0.71 | TDP1 (0.39) | ACHEGRM5ALDH1A1FFAR1CYP3A4 | |
| SCHEMBL1611056 | 0.71 | TDP1 (0.39) | ACHEALDH1A1CYP3A4TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387196-B1 | Complexes with optically active ligands, process for their preparation and their use | CIBA GEIGY AG (CH) | 1995-05-03 | — | — | EP | disclosed |
| EP-0254685-B1 | Complexes with optically active sugar ligands, process for their preparation and their use | CIBA GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5047557-A | Complexes having optically active ligands, a process for their preparation and their use | CIBA-GEIGY CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0387196-A1 | Complexes with optically active ligands, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1990-09-12 | — | — | EP | disclosed |
| US-4914196-A | CHIRAL REACTANTS FOR ALDEHYDES, KETONES, N-SUBSTITUTED IMINES | CIBA-GEIGY CORPORATION (US) | 1990-04-03 | — | — | US | disclosed |
| US-4826965-A | Metal complexes containing optically active sugar ligands, a process for their preparation and their use as chiral reactants for synthesis of alcohols and amines | CIBA-GEIGY CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0254685-A2 | Complexes with optically active sugar ligands, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1988-01-27 | — | — | EP | disclosed |