Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27090259 | 0.89 | ESR1 (0.75) | ESR1ESR2MAPTAPPNPC1 | |
| SCHEMBL2158298 | 0.88 | ESR1 (0.73) | ESR1ESR2MAPTAPPNPC1 | |
| SCHEMBL2248809 | 0.83 | ESR1 (0.81) | ESR1ESR2LMNAMAPTAPP | |
| SCHEMBL8034090 | 0.83 | ESR1 (0.81) | ESR1ESR2MAPTAPPNPC1 | |
| SCHEMBL27652633 | 0.82 | NPC1 (0.70) | LMNATP53MAPTPOLBNPC1 | |
| SCHEMBL9197043 | 0.82 | ESR1 (0.65) | ESR1ESR2TP53MAPTAPP | |
| SCHEMBL2248791 | 0.82 | NPC1 (0.65) | LMNATP53MAPTPOLBNPC1 | |
| SCHEMBL16894044 | 0.82 | ESR1 (0.79) | ESR1ESR2MAPTAPPNPC1 | |
| SCHEMBL16459336 | 0.81 | SMN1; SMN2 (0.64) | LMNATP53MAPTPOLBNPC1 | |
| SCHEMBL27672732 | 0.81 | TP53 (0.54) | ESR1ESR2LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422252-B1 | Method for detecting a substance using chemiluminescence | TORAY INDUSTRIES (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5206149-A | Reaction of peroxidase, oxidant, luminol and 2-hydroxy-9-fluorenone enhancer; chemiluminescence | TORAY INDUSTRIES, INC. (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0422252-A1 | Method for detecting a substance using chemiluminescence | TORAY INDUSTRIES, INC. (JP) | 1991-04-17 | — | — | EP | disclosed |