Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27090259 | 0.89 | ESR1 (0.75) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL4058336 | 0.88 | ESR1 (0.56) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL2158298 | 0.88 | ESR1 (0.73) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL8034090 | 0.83 | ESR1 (0.81) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL9196837 | 0.82 | ESR1 (0.66) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL29407133 | 0.81 | KDM4E (0.68) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL751653 | 0.81 | KDM4E (0.68) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL27090228 | 0.81 | ESR1 (0.96) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL2582987 | 0.80 | ESR2 (0.76) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL2158317 | 0.79 | ESR1 (1.00) | ESR1ESR2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422252-B1 | Method for detecting a substance using chemiluminescence | TORAY INDUSTRIES (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5206149-A | Reaction of peroxidase, oxidant, luminol and 2-hydroxy-9-fluorenone enhancer; chemiluminescence | TORAY INDUSTRIES, INC. (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0422252-A1 | Method for detecting a substance using chemiluminescence | TORAY INDUSTRIES, INC. (JP) | 1991-04-17 | — | — | EP | disclosed |