Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191850 | 0.83 | PTGS1 (0.53) | PTGS1CYP19A1 | |
| SCHEMBL9195197 | 0.83 | PTGS1 (0.66) | PTGS1PTGS2CYP19A1 | |
| SCHEMBL9193159 | 0.82 | PTGS1 (0.46) | PTGS1CYP19A1 | |
| SCHEMBL9193835 | 0.81 | PTGS1 (0.46) | PTGS1CYP19A1 | |
| SCHEMBL9192106 | 0.80 | KMT2A (0.58) | PTGS1PTGS2CYP19A1 | |
| SCHEMBL6340471 | 0.79 | PTGS1 (0.71) | PTGS1PTGS2CYP19A1 | |
| SCHEMBL9192586 | 0.78 | KMT2A (0.55) | PTGS1PTGS2CYP19A1 | |
| SCHEMBL2646659 | 0.76 | PTGS1 (0.56) | PTGS1PTGS2 | |
| SCHEMBL9193415 | 0.76 | CYP19A1 (0.49) | PTGS1CYP19A1 | |
| SCHEMBL9193200 | 0.74 | PTGS1 (0.63) | PTGS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423482-B1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1995-01-11 | — | — | EP | claimed |
| US-5094681-A | HERBICIDAL 5H-FURAN-2-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | claimed |
| EP-0423482-A1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1991-04-24 | — | — | EP | claimed |
| EP-0423482-B1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1995-01-11 | — | — | EP | disclosed |
| US-5207817-A | Heterocyclic amine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |
| US-5094681-A | HERBICIDAL 5H-FURAN-2-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0423482-A1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1991-04-24 | — | — | EP | disclosed |