Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197678 | 0.88 | CYP3A4 (0.57) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL11054487 | 0.87 | NPC1 (0.62) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL7314351 | 0.84 | NR3C1 (0.60) | HTTLMNANR3C1AHR | |
| SCHEMBL9197736 | 0.84 | USP2 (0.59) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6984531 | 0.80 | MEN1 (0.53) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL10648772 | 0.79 | NPC1 (0.67) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL6108475 | 0.77 | NR3C1 (0.50) | MEN1KMT2ASMN1; SMN2KDM4EPKM | |
| SCHEMBL10960859 | 0.75 | KMT2A (1.00) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL5022887 | 0.75 | NPC1 (0.65) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL14970890 | 0.75 | CYP3A4 (0.78) | NPC1MEN1KMT2ARAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292990-B1 | 4-Halopyridine-3-carboxamide compounds and herbicidal composition thereof | DAICEL CHEM (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-4978385-A | 4-halopyridine-3-carboxamide compounds and herbicidal compositions thereof | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1990-12-18 | — | — | US | disclosed |