Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196427 | 0.89 | MEN1 (0.50) | MEN1KMT2ARXFP1TYRALDH1A1 | |
| SCHEMBL4047966 | 0.82 | TYR (0.67) | MEN1KMT2ARXFP1TYRALDH1A1 | |
| SCHEMBL9195586 | 0.80 | MEN1 (0.47) | MEN1KMT2ARXFP1TYRALDH1A1 | |
| SCHEMBL18668918 | 0.79 | CASP3 (0.54) | RXFP1GRM5CASP3SMN1; SMN2ACHE | |
| SCHEMBL9197300 | 0.79 | KMT2A (0.57) | MEN1KMT2ARXFP1TYRALDH1A1 | |
| SCHEMBL28962650 | 0.79 | GRM5 (0.53) | MEN1KMT2ARXFP1TYRALDH1A1 | |
| SCHEMBL30216837 | 0.79 | GRM5 (0.53) | MEN1KMT2ARXFP1TYRALDH1A1 | |
| SCHEMBL18669095 | 0.77 | RPS6KA2 (0.53) | RXFP1TYRGRM5CASP3ACHE | |
| SCHEMBL29901110 | 0.76 | GRM5 (0.49) | MEN1KMT2ARXFP1TYRALDH1A1 | |
| SCHEMBL28855427 | 0.76 | GRM5 (0.49) | MEN1KMT2ARXFP1TYRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382687-B1 | Benzofused-N-containing heterocycle derivatives | BOEHRINGER INGELHEIM ITALIA (IT) | 1995-12-27 | — | — | EP | disclosed |
| US-5106851-A | Respiratory system disorders | ISTITUTO DE ANGELI S.P.A. (IT) | 1992-04-21 | — | — | US | disclosed |
| EP-0382687-A2 | Benzofused-N-containing heterocycle derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-08-16 | — | — | EP | disclosed |