Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 19/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200331 | 0.90 | TBXA2R (0.52) | TBXA2R | |
| SCHEMBL10437533 | 0.90 | TBXA2R (0.55) | TBXA2R | |
| SCHEMBL9201397 | 0.90 | TBXA2R (0.55) | TBXA2R | |
| SCHEMBL14415447 | 0.85 | TBXA2R (0.41) | TBXA2R | |
| SCHEMBL9195953 | 0.83 | TBXA2R (0.59) | TBXA2R | |
| SCHEMBL9718067 | 0.80 | TBXA2R (0.47) | TBXA2R | |
| SCHEMBL9203872 | 0.79 | TBXA2R (0.53) | TBXA2R | |
| SCHEMBL8870983 | 0.77 | TBXA2R (0.47) | TBXA2R | |
| SCHEMBL9698532 | 0.77 | TBXA2R (0.54) | TBXA2R | |
| SCHEMBL8870972 | 0.77 | TBXA2R (0.47) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391652-B1 | Interphenylène 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease | SQUIBB & SONS INC (US) | 1995-03-15 | — | — | EP | disclosed |
| US-5153327-A | 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5100889-A | Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1992-03-31 | — | — | US | disclosed |